Coronavirus Spike glycoproteins mediate the virus attachment to host cell surface receptors and facilitate the virus entry by assisting fusion between viral and host cell membranes. They are composed of two subunits, S1 and S2. The Spike protein of SARS-CoV-2 harbors furin cleavage sites, one being located at the boundary between S1 and S2. Spike glycoproteins are extensively studied as targets for antibodies, vaccine candidates or protease inhibitors, as examples.
Peptide length: 15 aa, 9aa for the C-terminal peptide
Gross peptide weight: not quantified
Synthesis scale: 5 µmol
Offset number: 7 aa
QC validation: MALDI-TOF QC on 10 % of peptides